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| Catalog_no | BDAB0044 |
| Product_name | Recombinant SARS-CoV-2(2019-nCoV) NSP3 protein |
| Category | 冠状病毒产品 |
| Applications | Immunogen |
| Size | 50ug/100ug/1mg |
| Price | 1800/2800/8800 |
| Specificity | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
| Formulation | Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5 |
| Source | E.coli |
| Storage_stability | Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt. |
| othername | nsp3,PL-PRO,Papain-like proteinase,X domain(Macro domain) |
| Background | The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells. |
| Notes | NSP3 |
| description | Recombinant SARS-CoV-2 NSP3 is produced by E.coli expression system and the target gene encoding Glu1024-Gln1198 is expressed with N-His Tag |
| Type | N-His |
| Purity | >90% as determined by SDS-PAGE |
| Molecular Weight | 22.03kDa |
| Instructions | 
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